EMBL Conference: Microglia: Guardians of the Brain
|Event Date/Time: Mar 26, 2014 / 8:00 am - (GMT)||End Date/Time: Mar 29, 2014 / 5:00 pm - (GMT)|
|Abstract Submission Date: Jan 16, 2014|
- Where do microglia come from?
- How do microglia contribute to neuronal development?
- How do microglia respond to neuronal injuries?
- How do microglia respond to disease?
Summary Microglia are phagocytic cells of hematopoietic origin that enter the brain and play important functions in both health and disease. Although discovered nearly one hundred years ago, microglia have only recently been appreciated to be highly dynamic cells that scan the brain to monitor and eliminate apoptotic, injured and sick neurons. Moreover, recent data indicate that microglia are able to sculpt developing neural circuits by engulfing synapses and contributing to synaptic pruning. These findings suggest that microglia are a jack-of-all-trades involved in brain surveillance, repair, and pruning. In this meeting we will bring together established and early stage researchers interested in microglia to better understand the many roles that these cells play in the healthy and sick brain.
Aims We aim to encourage researchers with different expertise and perspectives on microglia to exchange findings and ideas. In this way we hope to contribute to the development of a new community of researchers centred around these cells.