First Colloquium in Protein Structure, Function and Dynamics (UPR-PRC 2002)

Venue: Hilton Ponce and Casino

Location: Ponce, Puerto Rico, United States

Event Date/Time: Feb 05, 2003 End Date/Time: Feb 08, 2003
Registration Date: Jan 03, 2003
Early Registration Date: Dec 15, 2002
Abstract Submission Date: Dec 15, 2002
Report as Spam

Description

1st Colloquium in
Protein Structure, Function and Dynamics
February 5-8, 2003
Puerto Rico

The UPR-Protein Research Center (NIH-COBRE II) will celebrate its First Colloquium in Protein Structure, Function and Dynamics on February 5-8, 2003. We have invited over twenty speakers from abroad, including a Nobel Prize Laureate. A list of confirmed speakers is attached, as well as the preliminary program. It will be a truly international forum with guests from the US, Canada and Europe presenting forefront research in the area of protein chemistry. The main theme of the Colloquium is ¡§Frontiers in Protein Spectroscopy¡¨. It will include sessions in protein vibrational spectroscopy, X-ray crystallography, NMR, and time-resolved spectroscopy, among other interesting topics regarding protein research. All oral presentations are by invitation only and will be 40 minutes long (including questions). Due to the international nature of the meeting, all presentations will be in English.

Poster Presentations: All COBRE and non-COBRE researchers are invited to share their work related to protein structure, function and dynamics with the scientific community and our invited guests by participating in the poster session. The poster presentation should be up on Thursday February 6 and remain until Saturday afternoon, in order to stimulate as many interactions as possible between researchers and other interested community members. There will be a formal POSTER SESSION on Friday afternoon, when all authors will be required to be present to answer any questions. Due to the international nature of the meeting, all poster presentations will be in English. You should submit the title of the poster and an extended abstract no later than December 16, 2002. Acceptance of abstract will be notified to the author by December 20, 2002. COBRE will provide poster boards to all researchers that register on time (based on availability). The poster board space is 6 ft (wide) x 3ft (tall) (180 x 80cm). Please send the abstract electronically to: cobre2@uprm.edu. A copy of the Extended Abstract Form is included and will also be available at the Colloquium web page at http://cobre2.uprm.edu.

Confirmed Speakers

(Name, Affiliation and Title of Talk)

Denis Rousseau, Ph.D., Professor and Chair, Department of Physiology and Biophysics, Albert Einstein College of Medicine, New York, USA Resonance Raman on cytochrome oxidase and nitric oxide synthase

Werner Mäntele, Prof., Dr., Institut für Biophysik, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany Infrared Spectroscopy: Structural, functional, and dynamic information on proteins

Laurence Barron, B.Sc., D.Phil., F.R.S.E., Gardiner Professor of Chemistry,Department of Chemistry, University of Glasgow, UK Structure and behavior of unfolded proteins from Raman optical activity: new insight into the protein misfolding diseases

Laurence Nafie, Ph.D., Distinguished Professor of Chemistry and Biology, Syracuse University, USA Vibrational Circular Dichroism: From Amino Acids to Protein Pharmaceuticals

George Thomas, Jr., Ph.D., Professor of Basic Life Sciences and Head, Department of Cell Biology and Biophysics, University of Missouri, Kansas City, USA Protein Structure and Assembly in Viruses Probed by Raman and UV-Resonance Raman Spectroscopy

Robert Huber, Prof., Director Max Planck Institute for Biochemistry, Germany (1988 Nobel Laureate in Chemistry for the determination of the three-dimensional structure of a photosynthetic reaction centre) Molecular Machines for Protein Degradation

Jon Clardy,Ph.D., Horace White Professor of Chemistry, Department of Chemistry and Chemical Biology, Cornell University, USA Dihydroorotate dehydrogenase, Immunosuppression, and Malaria

Robert Stroud, Ph.D., Professor, Department of Chemistry and Biochemistry, University of California, San Francisco The Structure and selectivity of an ancient family of transmembrane channels

Mark Lemmon, Ph.D., Assistant Professor, Department of Biochemistry & Biophysics, University of Pennsylvania School of Medicine Structural view of how epidermal growth factor (EGF) activates its receptor

Nita J. Maihle, Ph.D., Professor of Biochemistry and Molecular Biology, Mayo Clinic School of Medicine, Rochester, MN Soluble EGFR/ErbB Isoforms: Form, Function and Clinical Utility

Joseph Bonaventura, Ph.D., Professor of Cell Biology, Duke University, North Carolina Reactions of Hemoglobin and Myoglobin with Nitric Oxide

Robin M. Hochstrasser-Donner, Donner Professor of Physical Sciences, Department of Chemistry, University of Pennsylvania Multidimensional infrared spectroscopy of peptides using femtosecond infrared pulse sequences

Majed Chergui, Ph.D., Professor of Experimental Condensed Matter Physics, Université de Lausanne, Switzerland Time-resolved X-ray absorption as a tool to study ultrafast transient phenomena in metalloproteins

Jean-Louis Martin, Director, Laboratory for Optics and Biosciences, Ecole Polytechnique, Paris, France Functional dynamics of heme-based protein sensors

William Eaton, M.D., Ph.D., Chief, Laboratory of Chemical Physics, National Institutes of Health,Bethesda, Maryland USA Single molecule fluorescence studies of protein folding

John Flanagan, Ph.D. Scientist, Biology Department, Brookhaven National Laboratory, NY Role of protein turnover in the control of metabolism: tale of two lysines

Walter Chazin, Ph.D., Chancellor¡¦s Professor of Biochemistry and Physics, Center for Structural Biology, Vanderbilt University, Nashville, TN, USA The importance of NMR for understanding the structural mechanisms of
multi-protein assemblies

Maurizio Brunori, Ph.D. Scientific Director of the Istituto Pasteur-Fondazione Cenci Bolognetti and Director of the Department of Biochemical Sciences ¡§A. Rossi Fanelli¡¨, University of Rome, ¡§La Sapienza¡¨ Structural dynamics of myoglobin

Ira Levin, Ph.D., Molecular Biophysics Section Chief, National Institutes of Health, Bethesda, Maryland Approaches to Vibrational and Visible Reflectance Spectroscopic Imaging of Biological Tissue

Lars Konnermann, Assistant Professor, Department of Chemistry, The University of Western Ontario, London, ON, Canada Use of mass spectroscopy to study protein folding

Michael Edidin, Ph.D., Professor, Department of Biology, Johns Hopkins U. Molecular mobility and aggregation in the ER membrane - Imaging the assembly and export of class I MHC molecules

Teresa Head-Gordon, Ph.D., Faculty Staff Scientist, Department of Bioengineering, University of California-Berkeley Title pending: (Protein Design)

Frank Jordan, Ph.D., Rutgers Board of Governors Professor of Chemistry and Director, Program in Cellular and Molecular Biodynamics, Rutgers, New Jersey Structural and Functional Studies of Protein-protein Communication in the Pyruvate Dehydrogenase Multienzyme Complex

William H. Woodruff, Laboratory Fellow, Biosciences Division, Los Alamos National Laboratory, Los Alamos, New Mexico The Scale of Things: Scaling Laws in Bioenergetics from Molecules to Ecosystems

Registration Form: Fill out the forms available through our web page and return it to our office by January 17, 2003, either by fax (787) 756-7717 or email to:
Att. Nancy Pláceres (nancy@adam.uprr.pr)
Puerto Rico COBRE II Program
University of Puerto Rico
PO Box 23334
Río Piedras, PR 00931-3334


UPR-Protein Research Center
First Colloquium in Protein Structure
Function and Dynamics Symposium


COBRE II Home

Home
Location
Speakers
Registration
Program
Abstract Submission
Links
Contact

WEDNESDAY, 5

Morning
External Advisory Board Meeting

2:00 pm - 9:00 pm
Arrival and check-in

7:30 pm - 9:00 pm
Registration and Welcome Reception

THURSDAY, 6

7:30 am - 8:30 am
Breakfast

8:30 am - 12:30 pm
Session I: Frontiers in Protein Vibrational Spectroscopy

Chairpersons: Dr. Reinhardt. Schweitzer-Stenner (UPR-Río Piedras) & Dr. Belinda Pastrana-Ríos (UPR-Mayagüez)

8:30 am - 8:40 am
Introduction

8:40 am - 9:20 am
Denis Rousseau, Department of Physiology and Biophysics, Albert Einstein College of Medicine, New York, USA. Resonance Raman on cytochrome oxidase and nitric oxide synthase

9:20 am - 10:00 am
Werner Mäntele, Institut für Biophysik, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany. Infrared Spectroscopy: Structural, functional, and dynamic information on proteins

10:00 am - 10:20 am
Coffee Break

10:20 am - 11:00 am
Laurence Barron, Department of Chemistry, University of Glasgow, UK

Structure and Behavior of Unfolded Proteins from Raman optical Activity: New Insight into the Protein Misfolding Diseases

11:00 am - 11:40 pm
Laurence Nafie, Department of Chemistry, Syracuse University, USA Vibrational Circular Dichroism: From Amino Acids to Protein Pharmaceuticals

11:40 pm ¡V 12:20 pm
George Thomas, Jr. Department of Cell Biology and Biophysics, University of Missouri, Kansas City, USA. Protein Structure and Assembly in Viruses Probed by Raman and UV-Resonance Raman Spectroscopy

12:30 pm - 2:00 pm
Lunch

2:00 pm ¡V 4:30 pm
Session II: Frontiers in Protein X-Ray Crystallography

Chairperson: Dr. Jorge Ríos-Steiner (UPR-Mayagüez)

2:00 pm ¡V 2:10 pm
Introduction

2:10 pm ¡V 2:50 pm
Robert Huber, Max Planck Institute for Biochemistry, Germany

Molecular Machines for Protein Degradation

2:50 pm ¡V 3:30 pm
Jon Clardy, Department of Chemistry and Chemical Biology, Cornell University, USA. Dihydroorotate Dehydrogenase, Immunosuppression, and Malaria

3:30 pm ¡V 3:50 pm
Coffee Break

3:50 pm ¡V 4:30 pm
Robert Stroud, Department of Chemistry and Biochemistry, University of California, San Francisco, USA. Membranes let in what they need, and exclude all else. But how?

7:00 pm ¡V 9:10 pm
Session III: Frontiers in Protein Research ¡V Mixed Topics

Chairpersons: Dr. Elsa Cora and Dr. Carmen Cadilla (UPR-Medical Sciences)

7:00 pm - 7:10 pm
Introduction

7:10 pm - 7:50 pm
Mark Lemmon, Department of Biochemistry & Biophysics, University of Pennsylvania School of Medicine, USA. Structural View of How Epidermal Growth Factor (EGF) Activates its Receptor

7:50 pm - 8:30 pm
Nita J. Maihle, Mayo Clinic School of Medicine, Rochester, MN. Soluble EGFR/ErbB Isoforms: Form, Function and Clinical Utility

8:30 pm - 9:10 pm
John Flanagan, Scientist, Biology Department, Brookhaven National Laboratory, NY. Role of protein turnover in the control of metabolism: tale of two lysines

FRIDAY, 7

7:30 am - 8:30 am
Breakfast

9:00 am - 12:30 pm
Session IV: Frontiers in Protein Time- Resolved Spectroscopy

Chairperson: Dr. Juan López Garriga (UPR-Mayagüez)

9:00 am - 9:10 am
Introduction

9:10 am - 9:50 am
Robin M. Hochstrasser-Donner, Department of Chemistry, University of Pennsylvania. Multidimensional Infrared Spectroscopy of Peptides using Femtosecond Infrared Pulse Sequences

9:50 am - 10:30 am
Majed Chergui, Université de Lausanne, Switzerland. Time-resolved X-ray Absorption as a Tool to Study Ultrafast Transient Phenomena in Metalloproteins

10:30 am - 10:50 am
Coffee Break

10:50 am - 11:30 am
Jean-Louis Martin, Director Laboratory for Optics and Biosciences, Ecole Polytechnique, Paris, France. Functional Dynamics of Heme-based Protein Sensors.

11:30 am - 12:10 pm
William Eaton, Chief, Laboratory of Chemical Physics, National Institutes of Health, Bethesda, Maryland USA. Single Molecule Fluorescence Studies of Protein Folding

12:10 pm ¡V 2:00 pm
Lunch

2:00 pm ¡V 3:30 pm
Session V: Frontiers in Protein Research ¡VMixed Topics

Chairperson: Dr. Enrique Meléndez (UPR-Mayagüez)

2:00 pm ¡V 2:10 pm
Introduction

2:10 pm ¡V 2:50 pm
Walter Chazin, Center for Structural Biology, Vanderbilt University, Nashville, TN, USA. The Importance of NMR for Understanding the Structural Mechanisms of Multi-protein Assemblies

2:50 pm ¡V 3:30 pm
Frank Jordan, Department of Chemistry, Rutgers, New Jersey, USA

Structural and Functional Studies of Protein-protein Communication in the Pyruvate Dehydrogenase Multienzyme Complex

3:30 pm ¡V 3:50 pm
Coffee Break

3:30 pm ¡V 5:30 pm
POSTER SESSION

7:30 pm - 9:30 pm
Dinner and Social Activity

SATURDAY, 8

7:30 am - 8:30 am
Breakfast

9:00 am - 3:40 pm
Session VI: Frontiers in Protein Research ¡V Mixed Topics

Chairpersons: Dr. Kai Griebenow (UPR-Río Piedras) & Dr. Gustavo López (UPR-Mayagüez)

9:00 am - 9:10 am
Introduction

9:10 am - 9:50 am
Maurizio Brunori, Dipartimento di Scienze Biochimiche, Universita' "La Sapienza", Roma, Italy. Structural Dynamics of Myoglobin

9:50 am - 10:30 am
Joseph Bonaventura, Duke University, North Carolina, USA. Reactions of Hemoglobin and Myoglobin with Nitric Oxide

10:30 am - 10:50 am
Coffee Break

10:50 am - 11:30 am
Lars Konermann, Department of Chemistry, The University of Western Ontario, London, ON, Canada. Use of Mass Spectroscopy to Study Protein Folding

11:30 am - 12:10 pm
Michael Edidin, Department of Biology, Johns Hopkins U. Molecular Mobility and Aggregation in the ER membrane - Imaging the Assembly and Export of Class I MHC Molecules

12:10 pm -1:40 pm
Lunch

1:40 pm - 2:20 pm
Teresa Head-Gordon, Department of Bioengineering, University of California-Berkeley. Physiochemical Minimalist Models and Protein Design

2:20 pm -3:00 pm
Ira Levin, National Institutes of Health, Bethesda, Maryland. Approaches to Vibrational and Visible Reflectance Spectroscopic Imaging of Biological Tissue

3:00 pm ¡V 3:40 pm
William H. Woodruff, Los Alamos National Laboratory, Los Alamos, New Mexico, USA. The Scale of Things: Scaling Laws in Bioenergetics from Molecules to Ecosystems

Evening TOUR TO ¡§LA PARGUERA¡¨ (PHOSPHORESCENT BAY)

Venue

1150 Caribe Avenue, Ponce, PR 00716
Ponce
Puerto Rico
United States
MORE INFO ON THIS VENUE

Additional Information

Registration Cost: Full: ƒÏ Non-student: $200.00 ƒÏ Student: $100.00 Includes: W, Reception & Th, F, S: Breakfast, Coffee breaks, Lunch) ƒÏ Friday Banquet Dinner: $40.00 p/p 1-Day Registration: ƒÏ Non-student: $60.00 per day ƒÏ Student: $30.00 per day ƒÏ Friday Banquet Dinner: $40.00 p/p To make hotel reservations, please call the Ponce Hilton at (787) 259-7676. The reservation code for the hotel is: COBRE 2 Group. Room rate during the conference (February 4 - 9) is $145.00 plus 16% tax. All hotel reservations must be made before January 3, 2002. After this date rates may vary. ƒÏ Poster boards will be provided by COBRE. For additional information please contact our Office at (787) 764-0000 Ext. 5807 or 765-5170 Ext. 2065, 2090 Or send an email to nancy@adam.uprr.pr