Intermediate Level Workshop on PK/PD Data Analysis: A Hands-on Course Using WinNonlin (Intermediate Level W)
Venue: Château de Maffliers
|Event Date/Time: Nov 10, 2003||End Date/Time: Nov 13, 2003|
|Early Registration Date: Aug 15, 2003|
Morning sessions consist of lectures dealing with choice of weights, goodness-of-fit, interpretation of computer output, experimental design and discrimination between rival models. Afternoon sessions are devoted to applying the methods discussed in the lectures to actual data, using WinNonlin. The participants work in pairs of two on each computer during the hands-on sessions. An extensive number of pharmacokinetic and pharmacodynamic models and data sets will be covered and users of software other than WinNonlin would also benefit from the methods discussed in the lectures and hands-on sessions. Two days are devoted to the analysis and interpretation of pharmacodynamic data such as steady-state data, indirect response models, link models, tolerance and rebound models, bi-phasic response data, physiological pharmacokinetic/ pharmacodynamic modelling etc. One afternoon session will be given as an introduction for participants with no, or very little, experience with WinNonlin. Participants are encouraged to bring their own kinetic/dynamic data.
The workshop is intended for individuals engaged in the pharmaceutical industry, regulatory agencies, contract research companies and universities, and for others who want to learn the aspects of model fitting. Previous participants have been toxicologists, kineticists, bioanalytical chemists, pharmacologists, clinical pharmacologists, anaesthesiologists, CRAs, and scientists from academia and regulatory agencies. Participants should have a background in pharmacokinetics, but those with limited experience would also benefit. The number of participants is limited.