HDL Cholesterol - Metabolic Pathways and Drug Developments (HDL 2004)

Venue: Royal Sonesta Hotel

Location: Cambridge, Massachusetts, United States

Event Date/Time: Mar 08, 2004 End Date/Time: Mar 09, 2004
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High cholesterol levels remain a leading cause for atherosclerosis and other cardiovascular diseases, despite the multitude of available therapeutics. In order to develop new pharmaceutical approaches for elevating HDL it is essential to gain a greater understanding of the various pathways in HDL -C metabolism and their regulation.
In it’s 5th year, this conference provides cutting-edge data on cholesterol efflux, transfer proteins, scavenger receptors, nuclear receptors, hepatic lipase, ABCA1 and apolipoprotein A.

Top experts from industry and academia present powerful strategies for reducing the risk of cardiovascular diseases by improving the atherosclerotic protection. Discover the latest developments in such topics as:

• The role of ceramide in the modulation of ABCA1-mediated cholesterol efflux
• Understanding the regulation of HDL-C by using natural genetic variation as a tool
• Analysis of SR-BI
• RXR agonists as regulators for dietary cholesterol
• Paraoxonase1 and it’s anti-atherosclerotic properties
• LXR in lipid metabolism
• HDL-raising drugs
• Hepatic Lipase modulates lipoprotein metabolism
• Molecular dynamics of ApoA-I
• ABCA1 / apolipoprotein interactions


5 CambridgeParkway
United States