2005 International Conference on Impact of Membrane Transporters in Drug Discovery & Development
February 23-25, 2005; San Diego, CA, USA


Wednesday, February 23, 2005

Basis of Membrane Transport Process (Ikumi Tamai, Tokyo University of Science; Chiba, JAPAN)

An Update of SLC Transporters (Hiroyuki Kusuhara, University of Tokyo; Tokyo, JAPAN)

ABC Transporters in Boundaries of Body Compartments (Bruno Stieger, University Hospital, Zurich, SWITZERLAND)

In vitro Methods for Transport Studies (Yuichi Sugiyama, University of Tokyo; Tokyo, JAPAN)

Methods for Estimation of Drug Transport: Transfection Systems, Intact Cells, and Whole Organs or Whole Body (Sandy Pang, University of Toronto, Toronto, ONT, CANADA)

Intestinal Transporters: Mechanisms and Involvement in Drug Absorption (Ikumi Tamai, Tokyo University of Science; Chiba, JAPAN)

Hepatic Transporters: Factors Affecting Systemic Bioavailability and Biliary Excretion (Yuichi Sugiyama, University of Tokyo; Tokyo, JAPAN

Thursday, February, 24, 2005

Evaluation of the Removal of Drugs by the First-pass Effect in Intestine and Liver (Sandy Pang, University of Toronto, Toronto, ONT, CANADA)

Renal Transporters Involved in the Urinary Excretion of Drugs (Hiroyuki Kusuhara, University of Tokyo; Tokyo, JAPAN)

Molecular Characteristics of Efflux Transporters at the Blood-brain Barrier (Hiroyuki Kusuhara, University of Tokyo; Tokyo, JAPAN)

Mechanisms of Transporter Gene Expression and their Effects on Membrane Transport Activity and Drug Pharmacokinetics (Jyrki J. Eloranta, Laboratory of Molecular Gastroenterology and Hepatology, University Hospital Zurich, SWITZERLAND)

In Vivo Consequence of Transporters and Approaches to Predict Inter-individual Variation and Drug Interaction (Yuichi Sugiyama, University of Tokyo; Tokyo, JAPAN)

Pharmacogenetics and SNPs of Transporters (Ikumi Tamai, Tokyo University of Science; Chiba, JAPAN).

Effect of Transporters on Intestinal and Hepatic First-pass Metabolism (Jiunn Lin, Merck & Co., Inc.; West Point PA)

Friday, February, 25, 2005

Pharmacotransport: Impact on the Drug Development Process (Willy Roth, Boehringer Ingelheim Pharma, GmbH & Co. KG, Biberach/Riss, GERMANY

Factors Based on Transporters that Cause Alteration of Absorption and Disposition of Drug Candidates During Discovery and Development Stage (Takayoshi Yoshikawa , Shionogi & Co. Ltd.; Osaka, JAPAN

Use of KO Mice, Transporter Expression Systems, Human Tissue and Cells for Evaluation of Contributed Transporters (Sonia M. de Morais, Pfizer Global Research and Development Groton Laboratories; Groton, CT)

JOIN ISE, Inc. in SAN DIEGO FOR BOTH EVENTS

ETS-2005 Registration: US $1500.00________ Transporters-2005: US $1500.00________

SPECIAL DISCOUNT-BOTH EVENTS US$2000.00________
Exhibitors: US $2000.00________

Academic/Government participants will receive a 50% discount.

Contact Nola Mahaney for Exhibitor or Sponsorship Opportunities at nola@isciencex.com, or phone (410) 869-9166); or visit www.isciencex.com/exhibitors .

Registration fee CTDD-2005 $1500.00 Pleae join ISE for both San Diego Events in February for a discounted fee of $2000.00