PPARs and Metabolic Disorders- Where Are We Now?

Venue: MIT Faculty Club

Location: Cambridge, Massachusetts, United States

Event Date/Time: Dec 13, 2004 End Date/Time: Dec 13, 2004
Registration Date: Dec 09, 2004
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GENFIT is pleased to invite you to the following event:
PPARs and Metabolic Disorders: Where are we now?
MIT Faculty Club – Cambridge, MA
December 13, 2004- 4.30pm to 7pm



Major pharmaceutical and biotech companies have invested a lot of money to develop PPARs compounds for potential therapies for diabetes and metabolic disorders but concerns over safety of such drugs may delay their entry on the market.
Pr.Fruchart and our panel of experts will highlight recent advances in the field of PPARs and their potential as druggable targets in a wide range of diseases including diabetes, insulin resistance, dyslipidemia, atherosclerosis and obesity.
We will also explore the advantages of developping multi modal drugs, such as dual PPARs, which are believed to have blockbuster potential to manage the Global Cardiovascular Risk.


4.30pm: Coffee and networking

4.50pm: Welcome remarks

5.00pm: PPAR alpha : still en vogue after so many years?
Prof. Jean-Charles FRUCHART, Ph.D, President-elect, International Atherosclerosis Society

5:30pm: Multi-modal drugs: the Holy Grail to manage the Global Cardiovascular Risk?
Dr Dean HUM, Ph.D, VP, Scientific Operations, GENFIT

6:00pm: The Expanding Clinical Scope of PPARa Agonists- An Impetus from the Fibrate Trials
Prof Sander ROBINS, M.D., Boston University School of Medecine

6:30pm: Q&A

6:45pm: Cocktail- Reception

Keynote Speaker:

Professor FRUCHART
Professor FRUCHART has devoted 30 years of a remarkable scientific career to the understanding of the molecular mechanisms that trigger and control metabolic diseases such as atherosclerosis, lipid disorders, and diabetes. His works have brought him to the head of the Atherosclerosis Department of the Pasteur Institute. The track record of his team is highlighted with major scientific breakthroughs that have brought to light the role of gene expression and regulation in those pathological mechanisms.
Throughout his scientific career, he has published over 500 articles in the most well known journals. Member ot the Executive Committee of the International Taskforce on Atherosclerosis Society, he was rewarded the Galien Prize in 1998 for his contribution to the development of innovative therapeutic molecules.
Professor FRUCHART is one of the founding members of GENFIT, ensuring the role of President.
Pr FRUCHART held a PharmD., a Ph.D. in Human Biology and Biochemistry and he is Professor of the University of Lille 2 and Associate Professor of the Pasteur Institute.
Pr FRUCHART has recently been elected President of the International Atherosclerosis Society

Registration is FREE but seating is LIMITED.
Please RSVP by e-mail to Yannick Foing at Yannick.Foing@genfit.com or call (617) 444-8416 before Dec.9th.
Do not hesitate to forward this invitation!

Directions to the MIT Faculty Club:
MIT Faculty Club, 50 Memorial Drive, 6th Fl., Cambridge, MA


50 Memorial Dr., 6th Fl.
United States