Event Date/Time: May 16, 2005
End Date/Time: May 18, 2005
RNA Interference has become one of the most powerful tools in functional genomics by providing a specific method to down-regulate genes and perturb pathways. However, other technologies have to be used in conjunction with RNAi in order to assess the phenotype that resulted from the knock-down or perturbation. Cambridge Healthtech Institute's Second Annual RNAi for Pathway Analysis meeting focuses on the integration of RNAi tools with other technologies, such as expression profiling, high-content cellular imaging, disease models, and pathway modeling. Specific case studies in functional genomics and target validation will be presented, as well as discussions on the current technological challenges in in vitro applications of RNAi, including delivery, stability and off-target effects.