Process Chemistry in the Pharmaceutical Industry

Venue: Radisson Hotel Miami Downtown

Location: Miami, Florida, United States

Event Date/Time: Mar 05, 2006 End Date/Time: Mar 08, 2006
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For the 5th annual ACS ProSpectives conference on Process Chemistry, chairs Margaret Faul, Director of Chemical Process R&D at Amgen, and Joseph Armstrong, Director of Process Research at Merck, have brought back their popular core curriculum with a few new twists.

As always, top scientists will speak on organometallics, synthesis and methodology, and six speakers from major pharmaceutical companies will present case studies that detail the methods they used to get novel compounds to market successfully. However, this year the conference will also include a session on green chemistry, with an emphasis on the development of environmentally friendly reactions during scale up, and a session on kinetics, so as to foster an in-depth mechanistic understanding of reactions.

Also new this year: the short course and the popular roundtable discussion will explore outsourcing and technology. The short course will include a session on process analytical technology (PAT), an aspect of process chemistry that the FDA increasingly emphasizes. The roundtable will explore the development of a comprehensive outsourcing strategy, and will identify critical factors in successful partnerships, including selecting and managing external vendors and managing the risk associated with outsourcing.

Confirmed Speakers to date:

Paul Wender of Stanford will keynote on synthesis, and Carsten Bolm of University of Aachen in Denmark will address asymmetric synthesis and enantioselective catalysis
Amir Hoveyda of Boston College will speak on the design and development of new selective transformations and their application to total synthesis of complex molecules of biological significance
Jon Ellman of UC Berkeley will speak on the development of practical and general new synthetic methods, in particular, methods for the asymmetric synthesis of amines and the development of synthetic applications of C-H activation
Donna Blackmond of Imperial College will speak on kinetic studies of complex catalytic organic reactions, with emphasis on application in the pharmaceutical process, and Paul Anastas of the ACS’s Green Chemistry Institute will speak on green chemistry
M. Bhupathy of Amgen will lead the "Outsourcing and Technology Transfer" roundtable, which will also include David Hoffman of Hovione, Ian Cottrell of Merck and Jeff Marcoux of Novasep.
Case Studies

Gerhard Penn of Novartis (Europe) will keynote on process chem, and Guy Humphrey of Merck, Vincent Mancuso of Eli Lilly, Michel Couturier of Pfizer, Chris Senanayake of Boehringer-Ingelheim and Steven Wittenberger of Abbott will all present case studies that detail the methods they used to successfully bring new compounds to market.
Short Course (optional)

Ambarish Singh of BMS will speak on Process R&D, Francis Van der Eycken of Mettler Toledo will speak on technology, and Peter van Broeck of J&J will speak on process analytical technology (PAT).


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Additional Information

Conference Fees: ACS Member $1,195 Non-Member $1,395 Pre-Conference Short Course $595