| Description |
ICCBM11 central scientific scopes:
Physics of the crystals, the crystallization process, and the physical chemistry of the mother liquors,
New ideas, approaches, reagents, and procedures for crystallizing proteins,
Unique areas of current interest or emerging challenges such as robotics, membrane protein crystallization, two dimensional crystals, microgravity, etc.,
The handling, manipulation, and modification of crystals to get them bigger or to yield improved data,
Important crystallization contributing to medical science and drug targets.
Preliminary Scientific Sessions
Physical-Chemistry Aspects
Obtaining first crystals via rational methods;
Physical chemistry and phase diagram in macromolecule crystallogenesis;
Complex crystal formation---structures---protein function.
New ideas and approaches
PCG for structural genomics : High-throughput methods for crystallization (Automation, Screening and Robotics);
Advanced methodology: Microminiaturized methods for crystallization;
Establishing a prominent crystallization database;
Macromolecule alteration for improving crystallizability.
Unique areas
New methods in the crystallization of membrane proteins, nucleic acids large macromolecule complexes (eg: protein-nucleic acid and receptors);
2-D crystals;
Rapid and large-scale protein expression and purification;
Growing large crystals for modern neutron methods.
Making full use of crystals
Heavy-atom derivative preparation;
Crystal improvements and handling; (including treatment for cryo-cooling And with Control of humidity);
Data collection and quality control.
Important crystallization contributing to medical science and drug targets
Crystallization of drug target for treating human diseases;
Inhibition of “in vivo” crystallization for treating pathologies.
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