Imaging Technology in Drug Discovery and Development

Venue: Hilton Washington DC/Silver Spring

Location: Silver Spring, Maryland, United States

Event Date/Time: Apr 06, 2006 End Date/Time: Apr 07, 2006
Registration Date: Apr 06, 2006
Abstract Submission Date: Mar 06, 2006
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Description

DAY 1

Thursday, April 6, 2006
7:00
Registration & Breakfast

8:00
Opening Remarks/Conference Goals
CONFERENCE CHAIR: Richard Margolin, M.D.,
Senior Director, CNS (North America), i3Research
Visiting Scholar, Laboratory of Molecular Imaging,
David Geffen School of Medicine, UCLA

8:15 KEYNOTE PRESENTATION:
Henry N. Wagner, Jr., M.D., Visiting Professor of Radiology, Director, Division of Nuclear Medicine, Vice Chairman for Technology and Business Development, Johns Hopkins Medical Institutions

9:00 TBA
Barbara Y. Croft, Ph.D., Cancer Imaging Program, National Cancer Institute

SESSION 1 - MODALITIES



9:30
Small Animal Optical Imaging

Umar Mahmood, M.D., Ph.D., Center for Molecular Imaging Research,

Massachusetts General Hospital, Harvard Medical School

10:00
30 MINUTE BREAK
10:30
The Role of PET in Drug Discovery with Focus on P-glycoprotein Functionality

Philip Elsinga, University Medical Center Groningen

11:00
Imaging the Esophagogastric Transit of Pharmaceutical Dosage Forms
Alan Perkins, PhD , FIPEM, ARCP, University Hospital of Nottingham

11:30
Oral Presentations from Selected Abstracts:



In Vivo Assessment of Myocardial Function in Spironolactone Treated Insulin Resistant Rats via Cine Magnetic Resonance Imaging (MRI)

Shawna Cooper, Sr. Research Specialist,

Department of Internal Medicine-ENDO

Sowers Lab, Harry S. Truman Veteran's Hospital



Imaging of Cancer-Induced Bone Destruction using Micro Computed Tomography

Andreas Evdokiou, The University of Adelaide



12:00
LUNCH


SESSION 2 – APPLICATIONS IN ONCOLOGY & CARDIOLOGY



1:30
Imaging Science and Oncologic Drug Development

G.J. Kelloff, National Cancer Institute

2:00
Optical Tomographic Small Animal Imaging System to Monitor Tumor Growth and Regression
Andreas H. Hielscher, Ph.D., Associate Professor Departments of Biomedical Engineering & Radiology, Columbia University
2:30
Non-invasive Bioluminescence Imaging of Spontaneous Tumorigenesis and Angiogenesis in Mice

Scott K. Lyons, Xenogen

3:00
In Vivo Monitoring of Human Embryonic Stem Cell-derived Graft Function in Living Animals using Optical Bioluminescence Imaging Technologies
Michelle Bradbury, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center

3:30
Refreshment Break

4:00
Tumor Imaging with Small Molecule Inhibitors

Padmaja Yalamanchili, Ph.D.,Bristol Myers Squibb Medical Imaging

4:30
Atheroma: Developments in Imaging Surrogates of Risk

Jonathan Gillard, BSc MD FRCR, University of Cambridge
5:00 KEYNOTE PRESENTATION:
Strategic Role of Imaging in Drug Development: Structure and Function
Helen Young, Ph.D., AstraZeneca
5:45
NETWORKING RECEPTION




DAY 2

Friday, April 7, 2006
7:00
Registration & Breakfast

SESSION 3– APPLICATIONS IN CNS


8:00 The Preclinical Development of CNS PET Radiotracers

Shailendra Patel, Ph.D., Merck
8:30 The Development of Amyloid Specific Imaging Agents for Application in Alzheimer's Disease

Andrew Lockhart, Ph.D., Neurology Biomarker Group, TMG, GlaxoSmithKline
9:00 PET Imaging of Amyloid Deposition using Pittsburgh Compound-B
Julie Price, University of Pittsburgh
9:30 Refreshment Break

10:00 In Vivo Drug Effects on Dopaminergic System

Bruce Jenkins, Ph.D., Instructor in Radiology, Director of Neurochemical Imaging
Department of Radiology, MGH, Harvard Medical School
10:30 Imaging Techonology: Applications in CNS

Richard Margolin, M.D., UCLA & i3Research
SESSION 4 – BIOMARKERS

11:00 Imaging Biomarkers in Drug Development:

An Overview of Opportunities and Open Issues

Mac Johnson, Millennium Pharmaceuticals
11:30 Unique Challenges in the Discovery of Novel Imaging Agents:

What is an Image-able Biomarker?

Michael Montalto, Ph.D., GE Global Research
12:00 LUNCH

SESSION 5 – CHALLENGES & OPPORTUNITIES

1:30 Utilizing Functional & Molecular Imaging Techniques

Thomas Zeffiro, M.D., Ph.D., Director, GU Center for Functional and Molecular Imaging, Georgetown University

2:00 Challenges and Opportunities for Positron-emission Tomography in Personalized Medicine

Suzanne V. Smith, Ph.D., Australian Nuclear Science & Technology Organization
2:30 Using Functional Magnetic Resonance Imaging in Awake Mice
Gerard B Fox, Ph.D., Project Leader, Global Pharmaceutical Discovery,
Abbott Laboratories
3:00 Refreshment Break
3:15 Commercialization of Research Tools
Richard Smith, Edwards Angell Palmer & Dodge
3:45 How Can Imaging Reshape Clinical Research by Accelerating Medical Discovery?

William C. Eckelman, Ph.D. Chief Scientific Officer, Molecular Tracer, LLC
4:15 CONFERENCE CONCLUDES


Click here to submit an abstract
Abstract Deadline: March 6, 2006

Venue

8727 Colesville Road
Maryland
United States
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