2006 Midwestern States Risk Assessment Symposium (MSRAS)

Venue: Hyatt-Regency Hotel Indianapolis

Location: Indianapolis, Indiana, United States

Event Date/Time: Apr 05, 2006
Abstract Submission Date: Apr 30, 2006
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The 2006 MSRAS will be held August 21-25 at the Hyatt-Regency Hotel in Indianapolis. This year’s agenda focuses on the complex toxicology and cleanup issues surrounding Trichloroethylene and Perchloroethylene. These issues will have a major impact on environmental policy in the coming years, including the derivation and use of cancer slope factors for these and other compounds. There is also a significant vapor intrusion component.

In addition to platform presentations and panel discussions, case studies will be presented which discuss some of the difficulties related to evaluating and managing TCE and PCE sites. Because the event is about applications of science rather than standard research, it has become a very important risk assessment event for those who are implementing hazardous waste cleanup programs. U.S. EPA Administrator Stephen Johnson has been invited by Governor Mitch Daniels to be the keynote speaker this year.

This event has been very successful in the past, with about 400 in attendance from all over the U.S. and Canada. This year’s event is sponsored by the Indiana Department of Environmental Management, Purdue University, U.S. EPA, The Halogenated Solvents Industry Alliance, the State Coalition for Remediation of Drycleaners, and others to be announced.

For questions about the event, please contact Sandie Meanor 317-232-8997, smeanor@idem.in.gov

Preliminary Agenda
2006 Midwestern States Risk Assessment Symposium

Note – Speaker TBA means that someone has been invited, but has not yet officially accepted the invitation.

Monday August 21, 2006

1:00 – 5:00 pm – Soil Gas Sampling Workshop, Classroom Session

1:00 – 4:00 pm - Dosimetric adjustments

This half-day training will focus on dosimetric adjustments encountered in routine dose response analyses in noncancer and cancer risk assessment. The training will cover dosimetric adjustments for inhalation exposure, including the calculation of target region-specific human equivalent concentrations (HECs) for exposure to vapor and particulates and duration adjustment. Oral dose adjustments from animals to humans, as done in cancer risk assessment, will also be covered. Participants will learn the basic concepts, the significance of conducting dosimetric adjustments, information resources, and adjustment calculations through class discussion using sample data. After the training, participants should be able to independently conduct dosimetric adjustment calculations for noncancer and cancer risk assessment.

Registration Fee $69.00

Tuesday August 22, 2006

8:00 am – 3:00 pm – Soil Gas Sampling Field Work

3:30 – 5:00 – Soil Gas Sampling Classroom Wrap-Up Session

8:00 am – 5:00 pm - Benchmark Dose Modeling

This full-day training course is designed to give an overview of benchmark modeling software for cancer and noncancer dose-response assessment, and provide hands-on experience in using the latest EPA BMDS software. This course is specifically designed for risk assessors who do not necessarily have a strong background in biostatistics. Through this training course, participants will learn the basic concepts of the BMD approach, necessary knowledge to successfully conduct BMD modeling, and appropriate application of BMD modeling results in cancer and noncancer dose-response assessment. The workshop will cover all the BMD models available in the current version of EPA’s BMDS software including continuous models, dichotomous models, nested models, and the cancer model. All the participants will practice selecting model parameters, running each BMD model and making judgments on the final BMD model results.

Registration Fee - $169.00

8:00 am – 5:00 pm - Noncancer and Cancer Risk Assessment

This course is designed as an introduction to cancer and noncancer risk assessment for the nonspecialist. The course begins with an overview of the National Academy of Science risk assessment paradigm, and presents basic related toxicology concepts. Methods for development of RfDs (noncancer risk values) are then presented, including identification of the critical effect, uncertainty factors, and the assumptions and limitations of the methods. The cancer risk assessment portion addresses the types of data relevant to cancer assessment and the basics of data evaluation. Use of Mode of Action Data, and principles for evaluation of Mode of Action in the cancer assessment are addressed, along with the methods for dose-response analysis. The course concludes with a discussion of risk characterization. The concepts presented in the course will be illustrated with examples and class exercises.

Registration Fee - $149.00

Wednesday August 23, 2006

8:00 – 8:30 – Opening Remarks

8:30 – 5:00 - Issues in Trichloroethylene Risk Assessment

Session Chair – Michael Dourson, PhD, Toxicology Excellence For Risk Assessment

8:30 – 9:00 - Science and Why It Is Important to Get It Correct - Shannon Cunniff, U.S. Department of Defense

9:00 – 9:30 - Status of the NAS TCE Review - Rogene Henderson, Chair of the National Academy of Science Panel Reviewing the National Center for Exposure Assessment TCE Risk Assessment

9:30 – 10:00 – Hazard identification - Sorting Through the Human and Experimental Animal Data - Invited Speaker TBA

10:00 – 10:30 – Break

10:30 – 11:00 - Usability of Epidemiology Studies - Jeff Mandel, Exponent, inc.

11:00 – 11:30 – Dose Response Assessment With Mode of Action Understanding of TCE - John Christopher, California EPA

11:30 – 12:00 - Exposure Assessment: Complete or Potentially Complete Pathways of Exposure - Bob Benson, U.S. EPA

12:00 – 1:30 Lunch

Speaker – Thomas Skinner, U.S. EPA Regional Administrator

1:30 – 2:00 – Trichloroethylene Case Study - Invited Speaker TBA

2:00 – 2:30 – Trichloroethylene Case Study –
The View-Master Site - Mike Poulson, Oregon DEQ and Jae Douglas, Oregon DHS

2:30 – 3:00 – Trichloroethylene Case Study - Invited Speaker TBA

3:00 – 3:30 – Break

3:30 – 4:45 – Panel Discussion

State Issues Associated With the TCE Risk Management

Moderator, Dr. Michael Dourson, Toxicology Excellence for Risk Assessment
Lorenz Rhomberg, Gradient Corporation
Paul Dugard, Halogenated Solvents Industry Alliance
Invited Federal Representative, TBA
Invited Federal Representative, TBA
Mike Poulson, Oregon DEQ
Invited State or Tribal Representative, TBA

4:45 – 5:00 - Conclusion by the Session Chair

5:30 – 7:00 – Dinner

Invited Keynote Speaker – U.S. EPA Administrator Stephen L. Johnson

Thursday August 24, 2006

8:30 – 9:00 –Preliminary Results Of the Soil Gas Sampling Workshop - Henry Schuver, U.S. EPA

9:00 – 5:00 - Risk Assessment and Risk Management Issues For Dry Cleaners and Vapor Intrusion

Session Chair – Inez Hua, PhD, Purdue University

9:00 – 9:30 – Judith Schreiber, PhD, NY Office of the Attorney General

9:30 – 10:00 – Developing a Risk Based State Dry Cleaning Program - Dr. Atul M. Salhotra, Risk Assessment and Management Group, inc.

10:00 – 10:30 – Break

10:30 – 11:00 – Invited speaker, TBA

11:00 – 11:30 –Chlorinated Solvents and Vapor Intrusion - Lenny Siegel, Center for Public Environmental Oversight

11:30 – 1:00 – Lunch

Lunch Speaker – Dr. Paul Dugard, Halogenated Solvents Industry Alliance

1:00 – 1:30 –Dry Cleaner Case Study - Theresa A. Evanson, Wisconsin Department of Natural Resources

2:00 – 2:30 – Perchloroethylene Risk Management Case Study – Linda S. Lee, PhD, Purdue University

2:30 – 3:00 – Dry Cleaner Case Study - Delonda Alexander, North Carolina Department of Environment and Natural Resources

3:00 – 4:15 – Panel Discussion

State Issues Associated With Dry Cleaner Cleanup Risk Management

Moderator - Bill Linn, State Coalition for the Remediation of Drycleaners
Paul Dugard, HSIA
Invited Federal Representative, TBA
Lenny Siegel, CPEO
Theresa A. Evanson, Wisconsin DNR
Delonda Alexander, North Carolina DENR

4:15 – 4:30 - Conclusion by the Session Chair

5:00 – 7:00 – Poster Session


Additional Information

Registration Regular - $250 Government/Student - $100