Neurotox 7 (Neurotox)
Venue: University of Portsmouth
|Event Date/Time: Sep 10, 2007||End Date/Time: Sep 13, 2007|
|Registration Date: Sep 06, 2007|
|Abstract Submission Date: Nov 17, 2006|
|Paper Submission Date: Nov 17, 2006|
This international conference is the seventh in the series and is concerned with the actions and toxicology of drugs and pesticides on the nervous system. It is organised on behalf of the BioActive Sciences and Pest Management Groups of SCI in association with the Royal Entomological Society. The scientific programme is arranged around a number of themes and comprises invited and offered papers. In addition there will be a poster session.
Aims of the Conference
Neurotox’07 will present the latest research in a number of related areas of neurotoxicology where applications of genomics, computational biology and molecular biology are rapidly advancing our knowledge of nervous system development, organisation and function and are also enhancing our understanding of the sites and modes of action of neurotoxicants. The conference will bring together scientists involved in basic research with those applying this work to tackle problems of resistance to drugs and pest control agents. The use of invertebrate and vertebrate models to investigate the differential toxicity necessary for developing novel pest control agents will be discussed. Neurotox’07 aims to disseminate state-of –the-art research in nerve function and neurotoxicology and elucidate ways in which this can be used to improve the control of parasitic diseases and invertebrate pests, particularly in tropical areas where these have significant impact on the quality of human life. The programme will be of interest to all neuroscientists and other researchers developing neuroactive molecules, including toxicologists from industry, research organisations, governmental laboratories and managers who wish to obtain an overview of this exciting field.
Themes of Neurotox 2007
Tropical pest toxicology and genomics.
Recent advances in the control of tropical pests made by exploiting the genome sequences of vectors will be presented and discussed in terms of the rational design of new neurotoxicants with greater specificity for the pest species.
Crop pest toxicology and genomics.
This theme will contain presentations and discussions on the use of genomic techniques to understand the mode of action of pesticides for crop pests and to provide a basis for resistance management and the design of new toxicants.
Parasite neurotoxicology and drug resistance.
This aspect of the conference will concentrate on the neurobiology of internal and external parasites and the development of chemical control strategies that target the excitable systems of these pests. Recent advances in the molecular neurobiology of parasites will be a highlight of this theme.
Molecular toxicology in silico
Tools based on molecular modelling, and informatics software have been widely applied in areas such as prediction of protein structures, in silico docking of small molecules, and the analysis of molecular structure and microarray expression data. These are being used to predict the ADME and toxicological profiles of candidate drugs and potential toxicants.
The use of neurotoxins to control parasites and arthropod pests raises concerns about their potential actions on vertebrate nervous systems. Recent findings in this area of vertebrate neurotoxicology will be presented and measures to improve their risk-assessment will be discussed.
Recent advances in toxinology.
This session will explore the discovery of new neurotoxins from animal, plant and microbial sources that may provide pesticide and drug leads, as well as reporting new findings regarding the mechanism of action of known neurotoxins.
Chairperson Peter Usherwood (University of Nottingham)
Proceedings Editor Ian Mellor (University of Nottingham)
Secretary Ian Mellor (University of Nottingham)
Local Secretary Graham Bremer (University of Portsmouth)
Treasurer Richard Greenwood (University of Portsmouth)
Royal Entomological Society organiser Lin Field (Rothamsted Research)
International Advisory Board
To be announced
The conference will be held on the University of Portsmouth’s Guildhall campus. This central venue provides modern lecture theatres and poster presentation facilities, all a stone’s throw from the sea. Portsmouth has a fascinating maritime history and the Historic Dockyard with HMS Victory, the Mary Rose and HMS Warrior is within walking distance of the campus. The nearby Gunwharf Quays is the centrepiece of Portsmouth Harbour and includes designer stores, cinema, comedy club, bowling alley and many bistros and bars. The Spinnaker Tower is also in Gunwharf and reflects the flavour of Portsmouth – old and new standing side by side.
Delegates will stay in Rees Hall, just fifteen minutes walk from the University campus and two minutes walk from the beach. Southsea is a Victorian seaside resort. There are four miles of coastline enhanced by open spaces, parks and gardens. A paradise for those early morning joggers! Rooms are single study bedrooms with en-suite facilities
Portsmouth is a one and a half hour train journey from London Waterloo, and is accessible from both London Heathrow and Gatwick airports. The city is well served by motorways and the nearest airport is Southampton Parkway, which receives some domestic and international flights