Molecular Targets for Cancer Prevention Diagnosis and Treatment (Tumor Targets)

Venue: Limassol

Location: Limassol, Limassol, Cyprus

Event Date/Time: Oct 07, 2007 End Date/Time: Oct 10, 2007
Registration Date: Sep 10, 2007
Early Registration Date: Jul 30, 2007
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Sunday, October 7, 2007
13:00 – 19:00 Registration
19:00 Reception (wine and cheese)
20:00 Keynote presentation
35 years of breast cancer chemoprevention
V. Craig Jordan, Vice President and Research Director for Medical Sciences , Fox Chase Cancer Center

Monday, October 8, 2007
Session 1
Cancer prevention in Europe
Moderators – Jaak Ph. Janssens
9:00 Welcoming Remarks
Charis Charalampous, Minister of Health of Cyprus
9:05 The politics and policies of cancer prevention in Europe
Adamos Adamou, Senator to the EU
9:10 Strategic plan for promoting science and technology in Cyprus Andreas Moleskis, Head of the Cyprus Planning Bureau
9:15 Funding opportunities by the Cyprus Research Promotion Organization (not confirmed)
Leonidas Antoniou, Acting Director of Cyprus Research Promotion Foundation
9:20 Welcome remarks, and an overview of the University of Cyprus
Constantinos Christofides, Vice Chancellor of the University of Cyprus
9:25 Conference objectives: Overview of molecular targets for the new era of anticancer research
Andreas I. Constantinou, Dean, Faculty of Pure and Applied Sciences, UCY
9:30 Overview of mechanisms of cancer chemopreventive agents
Gary D. Stoner, Professor, College of Medicine and Public Health, OSU
10:00 Lifestyle and Breast Cancer
Jaak Ph. Janssens, Editor, European Journal of Cancer Prevention
10:30 – 11:00 Coffee Break

Session 2
Molecular targets in lung and gastrointestinal cancer
Moderator – Silvio De Flora
11:00 Chemoprevention of cigarette-smoke related biomarkers and tumors
Silvio De Flora
11:30 Prevention of Gastrointestinal Tract Cancers with Berries and Berry Components
Gary D. Stoner
12:00 H. pilori as a target for cancer chemoprevention (not confirmed)
George Potamitis

12:30 – 15:00 Lunch break

Session 3
Molecular targets in breast, ovarian and cervical cancer
Moderator – V. Craig Jordan
15:00 Drug resistance to antihormonal chemoprevention
V. Craig Jordan
15:30 Equol reduces tamoxifen-induced DNA damage in breast, uterus, liver and PMNCs
Andreas Constantinou
16:00 Tam and soy effects in tamoxifen resistant tumors in mice
Debra Tonetti
16:30 Vaccination and screening for HPV in cervical cancer
Jack Cuzick
17:00 Characterization of the EMSY breast cancer gene
Tony Kouzarides
17:30 – 19:30 Poster Viewing

Tuesday, October 9, 2007
Session 4
Molecular targets in prostate cancer
Moderator – Omer Kukuc
9:00 am Soy isoflavones in prostate cancer prevention and treatment
Omer Kucuk
9:30 New Targets for Prostate Cancer Chemoprevention
Dave McCormick
10:00 Therapeutic targets in prostate cancer with focus on migration
Manolis Demetriou
10:30 – 11:00 Coffee break

Session 5
Molecular targets in colon and rectal cancer
Moderators – John D Potter / Michael Holick
11:00 Colorectal Neoplasia: what we know about genes and environment
John D. Potter
11:30 Vitamin D: its role in cancer prevention and treatment
Michael Holick
12:00 Efficacy and mechanism of action of vitamin D5 in breast cancer or Use of vitamin D analogs in prevention and therapy of breast cancer
Rajendra Mehta
12:30 VDR, vitamin D, p53 and cancer
Moshe Oren
13:00 – 15:00 Lunch break

Session 6
Molecular targets - targeted by the drug industry I
Moderator – Jacques Pouysségur
15:00 HIF1alpha as a prognostic, diagnostic or therapeutic target
Jacques Pouysségur
15:30 p53-MDM2 complex
Moshe Oren
16:00 – 16:30 Coffee break

Session 7
Awards and poster presentations
Moderator – Gary Stoner
16:30 Awards to student posters
Andreas Constantinou
16:40 Presentations of best posters
Students (to be named)
17:00 – 19:00 Open wine bar and viewing of posters

Wednesday, October 10, 2007
Session 8
Identification of new molecular targets (proteomics)
Moderator –Kyriacos Kyriacou
9:00 Latest advancements in proteomics and metabolomics
Kyriacos Kyriacou
9:30 Developing methods to profile cytochrome P450s from normal and tumour tissues
Chris Sutton
10:00 Proteomic approaches for cancer biomarker discovery
Eleftherios Diamandis
10:30 – 11:00 Coffee break

Session 9
Molecular targets -targeted by the drug industry II
Moderator – Jack Cuzick
11:00 Drug development: therapies based on inhibition of the EGFR family (Herceptin, Erbitux, Lapatinib)
Yosef Yarden
11:30 Regulation of cell proliferation by NF-kB
Evangelos Kolettas

Session 10
Identification and characterization of new chemopreventive agents
Moderator – Clarissa Gerhauser
12:00 Diet derived chemopreventive agents
Clarissa Gerhauser
12:30 System-wide pharmacoproteomic and toxicoproteomic studies of multiple cascading cellular events
Spiros Garbis
13:00 – 14:00 Lunch break
14:00 Immune responses to selected chemopreventive agents
Ourania Tsitsilonis
14:30 Antioxidants from green tea and pomegranate for chemoprevention of prostate cancer
Hasan Mukhtar
14:00-19:30 Excursion to Kykkos monastery and mountain villages
20:00 Gala Dinner

Thursday, October 11, 2007
10:00 – 16:00 Excursion to Paphos, Kourion and Kolossi castle



Additional Information

Abstracts submissions due: July 30, 2007 Please click here to submit your abstract Early Registration before July 30, 2007 - 400€ Late Registration before September 10, 2007 - 500€ Pre-Registration before September 24, 2007- 550€ On-Site Registration - 550€ Guest Registration 160€ Accepted Payment options: Credit card (American Express / Eurocard / Mastercard / Visa) Bank transfer Please click here to register The currency rate as of February 6th 2007 is 1 € = 1.29 US$.