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| Category |
Science: Biology
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| Category 2 |
Science: Life_Sciences
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| Contact |
Meyerhofstr. 1
69117 Heidelberg
Germany
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| Description |
Topics
The large amounts of data derived from next generation sequencing projects makes efficient data mining strategies necessary. In the course you will learn strategies for the analysis of mRNA-Seq data as well analysis pipelines for ChIP-Seq. These strategies include
• high efficiency mapping of raw sequence tags
• clustering of sequence tags
• data integration into up to date genome annotation
• down stream analysis of tag covered regions.
The course is based on real world examples. We will show the possibilities for extending genome annotation, splice variant detection and discovery of new transcriptional units. In addition the down stream biological mining of enriched regions from ChIP-Seq will be demonstrated. This will focus on transcription factor (TF) analysis in terms of TF overrepresentation in enriched regions and the discovery of functional motifs and patterns of TFs. New insights into biological mechanisms can be gained by overlaying data from different experiment types.
Programme
The first day will include a basic introduction plus hand on examples.
On the second day participants are encouraged to bring their own data.
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| Additional Information |
Registration
Online registration will be available soon.
• The application should contain a short CV, a statement about current research and a justification of interest in the course.
• The number of participants is limited to 10.
Confirmation and Payment
All registration fees include meals, local transportation and course material.
The registration fee should not be paid before acceptance to the course.
Scientific Organisers
Vladimir Benes, EMBL Heidelberg, Germany
Jonathon Blake, Genomatix, Germany
Martin Seifert, Genomatix, Germany
Christian Zinser, Genomatix, Germany
Hotel
Accommodation is included (2 nights) in the participation fee for the default dates of March 8 and 9, 2009. Rooms will be reserved at the ISG Hotel.
Local Transport
There will be shuttle buses running from the ISG hotel to EMBL and back mornings and evenings. A detailed schedule will be available closer to the event.
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