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SPECIFIC OBJECTIVES FOR THIS COURSE: DAY 1 - NEWER ANTIBACTERIAL AGENTS – Antibacterial spectrum of activity. Pharmacology. Indications and dosing recommendations. Side effects, adverse reactions and drug interactions. NEW OR EMERGING INFECTIOUS DISEASES: INFLUENZA; CLOSTRIDIUM DIFFICILE (CDI) - Etiology and pathogenesis. Clinical approach and methods of diagnosing these infections. Management, including prevention. UPDATE ON ANTIMICROBIAL RESISTANCE – Pattern of emergence of resistance of certain infecting bacteria. Epidemiology that may indicate potential resistance among organisms such as: Pneumococci; Enterococci; Gram negative bacilli. Therapeutic regimens, considering resistance. MENINGITIS AND MENINGOENCEPHALITIS - Epidemiology and the different types of meningitis. Clinical signs and symptoms of different types of meningitis. Indications for lumbar puncture (LP) and interpretations of results. Treatment options and the need for hospitalization and public health notification. DAY 2 - ADULT IMMUNIZATIONS, Part I – Adult immunization schedule. Timing and spacing of immunobiologics. Indications, efficacy, current recommendations for the following vaccine preventable diseases: Influenza, pneumococcus, pertussis. METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) - Epidemiology. Infections caused by MRSA. Risk factors and outcomes associated with MRSA control and treatment. ADULT IMMUNIZATIONS, PART II – Indications, efficacy, current recommendations for the following vaccine preventable diseases: Hepatitis A; Hepatitis B; Varicella-Zoster; Meningococcus; Human Papilloma Virus. CELLULITIS, NECROTIZING FASCIITIS AND THE DIABETIC FOOT ULCERS - Typical and atypical manifestations. Pathogenesis. Medical and surgical treatment. Prognosis. COMMUNITY ACQUIRED PNEUMONIA – Microbial causes. Strategies utilized to triage patients to appropriate level of care. Current diagnostic tests. Treatment regimens. DAY 3 - HELICOBACTER PYLORI INFECTION – Clinical manifestations. Diagnosis. Treatment. TUBERCULOSIS – Groups at risk for developing active tuberculosis. Principles of antituberculous therapy. Mantoux technique for tuberculin skin testing. Treatment of latent TB infection. HEPATITIS - Pathogenesis and clinical manifestations of hepatitis A, B, C, D or E. Differences in rates of complications. Treatment options for hepatitis B and C, rates of success. HIV PRIMER - Epidemiology of HIV infection. Recommendations for screening. Diagnostic tests (e.g. viral load, CD4 count), their application for disease management. Principles of antiretroviral treatment. HERPESVIRUS INFECTIONS - Clinically pertinent aspects of herpesvirus infections. Syndromes, clinical complications, attributes of recurrent disease. Management and use of anti-virals. Viruses to be covered include: Herpes simplex virus; Epstein-Barr virus; Cytomegalovirus; Varicella-zoster virus; HHV6. DAY 4 - URINARY TRACT INFECTION – Epidemiology. Attributes of lower tract and upper tract infections, reinfections, relapses. Chronic bacterial prostatitis. Approach to antimicrobial therapy, to include short course therapy. Approach to prevention. COMMON SKIN AND NAIL INFECTIONS - Bacterial infections. Fungal infections. Viral infections. Nail infections and other nail abnormalities. Parasitic infestations. INFECTIVE DIARRHEA - Presentation of toxigenic and invasive diarrhea. Food-borne pathogens. When to use fecal WBC, stool cultures, stool O&P examinations. Indications for antibiotic therapy. Antibiotic choices. ENDOCARDITIS PROPHYLAXIS GUIDELINES - Antibiotic prophylaxis of endocarditis, prosthetic joints. Data supporting prophylaxis. Identify patients for prophylaxis. Administration of prophylactic antibiotics. Prophylaxis in the allergic patient. ADVICE FOR THE TRAVELER - General preventive measures, what not to eat and drink. Immunizations. Prevention of malaria, diarrhea, other illnesses of travelers. Management of diarrhea of travelers.
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