From beads on a string to the pearls of regulation: the structure and dynamics of chromatin. A joint
|Event Date/Time: Aug 03, 2011||End Date/Time: Aug 04, 2011|
|Registration Date: Aug 02, 2011|
|Early Registration Date: Jul 04, 2011|
|Abstract Submission Date: Jun 01, 2011|
|Paper Submission Date: Jun 01, 2011|
The meeting will present advances in our understanding of chromatin structure and organization and the impact of these findings on our understanding of biological function. The meeting will bring together experts in the field to present recent advances in structural models for chromatin and the role of accessory factors that regulate its organisation. Topics to be covered will include the structure of the nucleosome core particle and the consequences resulting from histone modification and inclusion of histone variants, the analysis of nucleosome positioning in vivo and DNA sequence periodicities that influence location. Wider perspectives to be addressed include the relationship of chromatin and DNA repair, the role of high mobility group proteins and linker histones in chromatin organisation and function, and models for hierarchical assembly of chromatin. The meeting will mark the retirement of Professor Jean Thomas, who has made major contributions to the field.