Residual Moisture Testing - Proven Techniques (Biotech)
Venue: Online Event
|Event Date/Time: May 10, 2011||End Date/Time: May 10, 2011|
Monitoring and controlling residual moisture in powders, lyophilized solids, foods, etc can be a critical factor in achieving and maintaining quality products throughout their expected shelf life. Improper levels of moisture in products can result in poor powder flow properties, spoilage, polymorph changes, changes in compaction properties, microorganism growth promotion, higher degradation kinetics, and in the case of freeze-dried products, loss of physical structure and changes in reconstitution properties.
There are several methods typically employed to determine residual moisture, and the choice of method will be based on the sample tested, the level of residual moisture present, and the accuracy and precision required for testing. Additionally, many of these methods require a skill and knowledge in preparing and testing the samples if accurate results are to be achieved. In fact, in many cases, samples containing very low residual moisture, as in the case with freeze-dried products, accurate results for residual moisture are not achieved simply due to improper sample preparation and handling. Additionally, inaccurate and or imprecise results will be obtained if the correct method for testing residual moisture is not chosen.
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