NGS platforms now generate terabytes of genomic data, calling into question: What is the best way to benefit from this data bonanza? CHI’s Next-Generation Sequencing Data Management combines unique perspectives from a variety of researchers, engineers, biostatisticians, and software developers involved with NGS data management. This team of scientists will present case studies creating a common ground on which to explore how best to store, transfer, and analyze NGS data sets with the common goal of turning data into knowledge.