Predictive Functional Tissue Models: Moving into the Third Dimension of Drug Discovery and Developme

Venue: Omni Parker House

Location: Boston, Massachusetts, United States

Event Date/Time: Nov 17, 2011 End Date/Time: Nov 18, 2011
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Description

Compared to traditional cell-based assay monolayers, three-dimensional (3D) models more closely mimic native tissues. 3D tissue models provide a means for systematic, repetitive, and quantitative investigation of drugs, serving as platforms for screening of drugs as well as pharmacokinetic and pharmacodynamic analysis of drugs. That said, creating the more biologically relevant third dimension of tissue models requires a multidisciplinary approach and multidisciplinary expertise. Cambridge Healthtech Institute’s Predictive Functional Human Tissue Models: Moving into the Third Dimension of Drug Discovery and Development weaves together engineers, biologists, and pharmacologists. As with any 3D model, each specialty provides insights into the complete system advancing drug discovery and development, from designing the bioreactors, developing the 3D models, studying healthy versus diseased states, to utilizing drug screening assays.

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