Cellular function requires the spatial and temporal coordination of complex processes over a remarkable range of length and time scales. Structural biology — including X-ray, EM and NMR approaches — has been instrumental in contributing to our mechanistic understanding of catalysis, molecular recognition and regulation, as well as in providing unique insights into modulating these processes to support therapeutic intervention. As these structural approaches have continued to mature, they have moved out of the realm of the specialist and are now an essential and indispensible part of modern biological discovery. The future promise of structural biology rests on our ability to integrate atomic resolution knowledge with results derived from cutting-edge microscopies and spectroscopies, as well as complementary genetic, biochemical and chemical biological methodologies. This symposium will highlight the power of multi-disciplinary, multi-scale integrative approaches for understanding and manipulating fundamental biological processes, including cell motility, chromosome maintence, gene regulation and membrane-associated phenomena. Participants will also have an opportunity to broaden their appreciation of advances in structural biology that can be used for studying complex cellular systems via the concurrent meeting on High-Throughput Structural Biology, which will share a keynote address and two plenary sessions with this meeting.

This meeting is held jointly with the Keystone Symposia meeting "High-Throughput Structural Biology." Registering for one meeting in a set of joint meetings enables participateion in sessions of the other, pending space availability. Other deadlines: Abstract & scholarship - September 22, 2011 Late-breaking abstract - October 25, 2011