Keystone Symposia: Sirtuins in Metabolism, Aging and Disease (Sirtuins in Metaboli)

Venue: Granlibakken Resort

Location: Tahoe City, California, United States

Event Date/Time: Feb 12, 2012 End Date/Time: Feb 16, 2012
Registration Date: Feb 12, 2012
Early Registration Date: Dec 12, 2011
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Description

Sirtuins comprise a unique class of NAD+-dependent enzymes that modify multiple protein substrates to execute diverse biological functions. Sirtuins are key regulators of clinically important cellular and organismal processes including metabolism, cell division and aging. The desire to understand the important determinants of human health and lifespan has resulted in a firestorm of work on the seven mammalian sirtuins in the past decade. The implication of sirtuins in medically important areas such as diabetes, cancer, cardiovascular dysfunction and neurodegenerative disease has catapulted them to a prominent status as potential targets for nutritional and therapeutic development. The Keystone Symposia meeting on Sirtuins in Metabolism, Aging and Disease will address fundamental questions on the regulation, biochemical, molecular and cellular mechanisms and pathways of sirtuins. The significance of sirtuin-dependent regulation of homeostasis with respect to diverse biological organisms will be discussed. We envision that this meeting will evaluate the relevance of sirtuin biology in various human conditions, and provide a unique environment for discussing specific therapeutic strategies.

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Additional Information

Other deadlines: Abstract & scholarship - October 12, 2011 Late-breaking abstract - November 11, 2011