Keystone Symposia: G Protein-Coupled Receptors: Molecular Mechanisms and Novel Functional Insights (G Protein-Coupled Re)

Venue: Fairmont Banff Springs

Location: Banff, Alberta, Canada

Event Date/Time: Feb 17, 2012 End Date/Time: Feb 22, 2012
Registration Date: Feb 17, 2012
Early Registration Date: Dec 19, 2011
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The seven transmembrane-spanning G protein-coupled receptors (GPCRs) are the largest superfamily of receptors in the human genome, are involved in virtually all physiological processes and represent the targets for at least 30% of all current medicines. Recent years have witnessed the coalescing of a number of important paradigms, including ligand-biased signaling, allosteric modulation and receptor dimerization, with substantial advances in structural determination, chemical biology and in vivo approaches to studying GPCR function. These developments will undoubtedly have a profound impact on future approaches to GPCR-based drug discovery. This meeting will focus on the interplay between these developments, and how they can be exploited to advance the translational application of cutting-edge GPCR-based research.