Keystone Symposia: Ubiquitin Signaling (Ubiquitin Signaling)

Venue: Whistler Conference Centre

Location: Whistler, British Columbia, Canada

Event Date/Time: Mar 18, 2012 End Date/Time: Mar 23, 2012
Registration Date: Mar 18, 2012
Early Registration Date: Jan 18, 2012
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Description

Post-translational modifications of cellular proteins by ubiquitin and ubiquitin-like modifiers regulate a variety of functions in the cell. A crucial aspect of signaling through ubiquitin and Ubls is the presence of modular binding domains that recognize particular types of ubiquitin signals. Such molecular coupling creates an attractive “decoding” mechanism for responding to alterations in the cellular microenvironment and regulating physiological and pathophysiological conditions. In this meeting, we will discuss the major challenges in the field including detection of endogenous ubiquitination events, functional aspects of novel types of ubiquitin chains and their recognition by selective binding domains, and high-throughput technologies for comprehensive analysis of Ub modifications. The intersection between the deregulated ubiquitin signaling, pathogenesis of human diseases and therapies targeting the Ub system will be explored. The program offers a possibility for young scientists to present their own work and engage in discussions on the emerging topics in the field. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on NF-kB Signaling and Biology: From Bench to Bedside, which will share a keynote address and three plenary sessions with this meeting.

Venue

Additional Information

This meeting is held jointly with the Keystone Symposia meeting "NF-kappaB Signaling and Biology: From Bench to Bedside." Registering for one meeting in a set of joint meetings enables participation in sessions of the other, pending space availability. Other deadlines: Abstract & scholarship - November 16, 2011 Late-breaking abstract - December 20, 2011