Fragment-Based Drug Discovery

Venue: San Diego

Location: San Diego, California, United States

Event Date/Time: Apr 17, 2012 End Date/Time: Apr 18, 2012
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Description

Finding fragments by various screening methods has become an established practice. Each of the technologies used have a different set of advantages and disadvantages. Questions such as how to select the most suitable projects, how and when to use screening methods such as crystallography, NMR, SPR or mass spec either as a standalone technique or in combination and how to correctly predict binding at active sites will be addressed in this meeting. In addition, new challenges are arising and will be discussed, such as fragment docking, fragment library design, ligand efficiency, fragment selectivity and specificity.

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