Event Date/Time: Apr 04, 2013
End Date/Time: Apr 09, 2013
Early Registration Date:
Feb 04, 2013
Understanding the mechanisms by which tolerance is induced and circumvented is important towards developing new therapies for autoimmune disorders. While significant progress has been made in understanding the basic processes of both central and peripheral tolerance, the integration of these mechanisms in the context of the pathogenesis of autoimmunity is less well deciphered. In the past few years, considerable effort has been made in bringing together the fundamental mechanisms, the genetics and genomics, the cellular players, and the clinical features of disease towards developing novel therapeutic strategies. These efforts have also advanced our understanding of the pathogenesis of autoimmunity and revealed new players and potential therapeutic strategies in treatment of autoimmunity. The goal of this meeting is to bring together the scientist and clinician to discuss what we are learning from the information obtained from mouse models, patient studies and the use of novel targeted therapies. Both common and unique immune-mediated mechanisms leading to autoimmune diseases will be highlighted. The meeting will cover advances in genomic and cellular approaches, biomarker discovery, and in targeted therapies. The accompanying workshops will be designed to promote interactions and collaborations between academic and R & D scientists to respond to the challenges in this area.
Scientific Organizers: Juan Rivera, Virginia Pascual and David M. Lee